以下信息为主动公开的研究生招生宣传信息
目录
黄友华   更新日期: 2025年11月21日
黄友华,男,汉族,1981年9月生,湖北巴东县人,群众,博士研究生学历,理学博士,研究员,博导。
工作单位   云鼎国际4118
邮政编码  510642
通讯地址  广州市天河区五山路483号第一教学楼
邮箱地址  huangyh@scau.edu.cn
个人简介
黄友华,研究员,博士生导师,广东省特支计划百千万工程青年拔尖人才。研究方向为鱼类抗病毒免疫及生物防控。现主要聚焦于鱼类病毒致病机制、宿主免疫应答机制及免疫防控等方面开展工作。主持国家自然科学基金面上项目,重点研发项目子课题,广东省特支计划百千万工程青年拔尖人才项目等,研究成果在包括Nature communications、Journal of Virology、Cellular Microbiology、Frontiers in Immunology、Frontiers in Microbiology、Fish and shellfish immunology、Apoptosis、Aquaculture等杂志发表论文30余篇,参与获得授权专利8件,参与编写专著3部。
工作经历
2017.09-今              云鼎国际4118                      教授
2010.12-2017.09     中国科公司南海海洋研究所     副研究员
2010.04-2010.12     中国科公司南海海洋研究所     助理研究员
2007.09-2010.03     中山大学                            博士后
教育经历
2002.09-2007.07  中国科公司水生生物研究所  水生生物学   博士
1998.09-2002.07  华中师范大学                   生物教育      学士
获奖荣誉
广东省特支计划百千万工程青年拔尖人才
社会、学会及学术兼职
国家自然科学基金项目同行函评专家, Fish & Shellfish Immunology,Aquaculture等多个SCI杂志审稿人。
研究领域
研究方向及领域
鱼类抗病免疫应答机制及病原致病机理:
解析特色淡水鱼类和海洋鱼类抗病毒分子机制,鱼类病毒免疫逃逸分子机制;
鱼类免疫防控策略:
病毒疫苗研发、免疫增强剂及抗病毒中草药成分筛选及应用。
科研项目
主持国家自然基金面上项目,国家重点研发项目子课题,广东省自然基金面上项目,广东省特支计划百千万工程青年拔尖人才项目,参与国家自然科学基金重点项目。
发表论文
1. Zhao Z#, Huang Y#, Liu C#, Zhu D#, Gao S#, Liu S, Peng R, Zhang Y, Huang X, Qi J, Wong CCL, Zhang X, Wang P, Qin Q, Gao GF. Near-atomic architecture of Singapore grouper iridovirus and implications for giant virus assembly. Nat Commun. 2023 Apr 12;14(1):2050.
2. Xu W, Zhang Z, Lai F, Yang J, Qin Q, Huang Y**, Huang X*. Transcriptome analysis reveals the host immune response upon LMBV infection in largemouth bass (Micropterus salmoides). Fish Shellfish Immunol. 2023 Jun;137:108753.
3. Zhang Y, Gao X, Yang X, Wang Y, Wang W, Huang X, Qin Q**, Huang Y*. Singapore Grouper Iridovirus VP131 Drives Degradation of STING-TBK1 Pathway Proteins and Negatively Regulates Antiviral Innate Immunity. J Virol. 2022 Oct 3:e0068222.
4. Zhi L, Wang W, Zheng J, Liu S, Zhou S, Qin Q, Huang Y**, Huang X*. Grouper TRIM23 exerts antiviral activity against iridovirus and nodavirus. Front Immunol. 2022, 13:985291.
5. Guo X, Wang W, Zheng Q, Qin Q, Huang Y**, Huang X*. Comparative transcriptomic analysis reveals different host cell responses to Singapore grouper iridovirus and red-spotted grouper nervous necrosis virus. Fish Shellfish Immunol. 2022 Sep;128:136-147.
6. Wang W, Zhang Y, Guo X, Xu W, Qin Q, Huang Y**, Huang X*. Singapore grouper iridovirus infection counteracts poly I:C induced antiviral immune response in vitro. Fish Shellfish Immunol. 2023 Apr;135:108685.
7. Zhang Y, Wang L, Zheng J, Huang L, Wang S, Huang X, Qin Q*, Huang Y*. Grouper Interferon-Induced Transmembrane Protein 1 Inhibits Iridovirus and Nodavirus Replication by Regulating Virus Entry and Host Lipid Metabolism. Front Immunol. 2021 Mar 9;12:636806.
8. Liu ZT, Zhang X, Zhang Y, Qin QW, Huang XH, Huang YH. Establishment of a cell line from the head kidney of giant grouper (Epinephelus lanceolatus) and its susceptibility to fish viruses. Aquaculture Reports. 2021, 21: 100899.
9. Huang YH, Huang LW, Zhang Y, Zheng Q, Xu LW, Qin QW, Huang XH, Development of a sea perch (Lateolabrax japonicus) fry cell line and its application to the study of fish virus-host interactions. Aquaculture. 2021, 736127.
10. Huang XH, Wei JG, Zheng Q, Zhang Y, Zhu WB, Liu JC, Hou YX, Qin QW, Huang YH. Isolation, identification and genomic analysis of an ISKNV-type megalocytivirus from spotted knifejaw (Oplegnathus punctatus). Aquaculture. 2021, 532: 736032.
11. Huang Y, Zhang Y, Zheng J, Wang L, Qin Q, Huang X. Metabolic profiles of fish nodavirus infection in vitro: RGNNV induced and exploited cellular fatty acid synthesis for virus infection. Cell Microbiol. 2020 Sep;22(9):e13216.
12. Huang Y, Zhang Y, Liu Z, Liu C, Zheng J, Qin Q, Huang X. Autophagy Participates in Lysosomal Vacuolation-Mediated Cell Death in RGNNV-Infected Cells. Front Microbiol. 2020 Apr 30;11:790.
13. Lv S, Zhang Y, Zheng J, Huang X, Huang Y**, Qin Q*. Negative regulation of the interferon response by finTRIM82 in the orange spotted grouper. Fish Shellfish Immunol. 2019, 88:391-402.
14. Zhang Y, Wang L, Huang X, Wang S, Huang Y**, Qin Q*. Fish Cholesterol 25-Hydroxylase Inhibits Virus Replication via Regulating Interferon Immune Response or Affecting Virus Entry. Front Immunol. 2019, 10:322.
15. Liu J, Huang Y**, Huang X, Li C, Ni SW, Yu Y, Qin Q*. Grouper DDX41 exerts antiviral activity against fish iridovirus and nodavirus infection. Fish Shellfish Immunol. 2019, 91:40-49.
16. Huang Y, Zhang J, Ouyang Z, Liu J, Zhang Y, Hu Y, Huang X, Qin Q*. Grouper MAVS functions as a crucial antiviral molecule against nervous necrosis virus infection. Fish Shellfish Immunol. 2018.72:14-22.
17. Liu J, Huang X, Yu Y, Zhang J, Ni S, Hu Y, Huang Y**, Qin Q*. Fish DDX3X exerts antiviral function against grouper nervous necrosis virus infection. Fish Shellfish Immunol. 2017 Dec;71:95-104.
18. Yu Y, Huang X, Liu J, Zhang J, Hu Y, Yang Y, Huang Y**, Qin Q. Fish TRIM32 functions as a critical antiviral molecule against iridovirus and nodavirus. Fish Shellfish Immunol. 2017 Jan;60:33-43.
19. Huang Y, Zhang J, Liu J, Hu Y, Ni S, Yang Y, Yu Y, Huang X, Qin Q. Fish TRIM35 negatively regulates the interferon signaling pathway in response to grouper nodavirus infection. Fish Shellfish Immunol. 2017, 69:142-152.
20. Huang Y, Yang M, Yu Y, Yang Y, Zhou L, Huang X, Qin Q. Grouper TRIM13 exerts negative regulation of antiviral immune response against nodavirus. Fish Shellfish Immunol. 2016, 55:106-15.
21. Huang Y, Yu Y, Yang Y, Yang M, Zhou L, Huang X, Qin Q. Fish TRIM8 exerts antiviral roles through regulation of the proinflammatory factors and interferon signaling. Fish Shellfish Immunol. 2016, 54:435-44.
22. Huang Y, Yu Y, Yang Y, Yang M, Zhou L, Huang X, Qin Q. Antiviral function of grouper MDA5 against iridovirus and nodavirus. Fish Shellfish Immunol. 2016, 54:188-96.
23. Huang Y, Ouyang Z, Wang W, Yu Y, Li P, Zhou S, Wei S, Wei J, Huang X, Qin Q. Antiviral role of grouper STING against iridovirus infection. Fish Shellfish Immunol. 2015, 47(1):157-67.
24. Huang Y, Huang X, Cai J, OuYang Z, Wei S, Wei J, Qin Q. Identification of orange-spotted grouper (Epinephelus coioides) interferon regulatory factor 3 involved in antiviral immune response against fish RNA virus. Fish Shellfish Immunol. 2015, 42(2):345-52.
25. Huang Y, Huang X, Yang Y, Wang W, Yu Y, Qin Q. Involvement of fish signal transducer and activator of transcription 3 (STAT3) in nodavirus infection induced cell death. Fish Shellfish Immunol. 2015, 43(1):241-8.
26. Huang YH, Huang XH, Ouyang ZL, Wei SN, Guo CY, Qin QW. Development of a new cell line from the snout of giant grouper, Epinephelus lanceolatus (Bloch), and its application in iridovirus and nodavirus pathogenesis. Aquaculture. 2014, 432: 265-272.
专著教材
参与编写专著 《鱼类细胞培养理论与技术》、《鱼病学》和《水产动物免疫学》。
科研创新
参与获授权发明专利8件。
1.一种鞍带石斑鱼头肾细胞系及其构建方法和应用,CN112941011 (排名第一)
2.抗大口黑鲈虹彩病毒的单克隆抗体及其应用,CN114230660B (排名第二)
3.一种石斑鱼 piscidin4 多肽及其应用,CN105801680B (排名第三)
4.一种石斑鱼 Epinecidin-1 多肽及其应用,CN105777887B (排名第三)
5.一种枯草芽孢杆菌 7K 及应用,CN107858302B (排名第四)
6.一种石斑鱼虹彩病毒亚单位疫苗制备方法和应用,CN108079287B(排名第五)
7.一种石斑鱼虹彩病毒灭活疫苗的制备方法,ZL201110110399 (排名第五)
8.一种石斑鱼虹彩病毒囊膜蛋白的提取方法,ZL201110110422 (排名第五)
教学活动
现主要讲授本科生《生物信息学》、《水产动物疾病防治学》、《水产养殖学导论》和研究生《水生动物病害与免疫防控》、《水生动物病原学》等课程。
指导员工
已毕业和在读研究生共10名, 多人获国家奖学金及校级优秀毕业生称号。
我的团队
小伙伴们,看过来,这里有基础研究,也有应用研究。不论你是本科生还是研究生,都欢迎成为我团队的一员,一起探索小鱼儿抗病奥秘和防控妙招!
在这里,只要你相信“天道酬勤”,你就一定会“鱼跃阔海”!
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