目录
2010.12-2017.09 中国科公司南海海洋研究所 副研究员
2010.04-2010.12 中国科公司南海海洋研究所 助理研究员
2007.09-2010.03 中山大学 博士后
1998.09-2002.07 华中师范大学 生物教育 学士
鱼类抗病免疫应答机制及病原致病机理:
解析特色淡水鱼类和海洋鱼类抗病毒分子机制,鱼类病毒免疫逃逸分子机制;
鱼类免疫防控策略:
病毒疫苗研发、免疫增强剂及抗病毒中草药成分筛选及应用。
2. Xu W, Zhang Z, Lai F, Yang J, Qin Q, Huang Y**, Huang X*. Transcriptome analysis reveals the host immune response upon LMBV infection in largemouth bass (Micropterus salmoides). Fish Shellfish Immunol. 2023 Jun;137:108753.
3. Zhang Y, Gao X, Yang X, Wang Y, Wang W, Huang X, Qin Q**, Huang Y*. Singapore Grouper Iridovirus VP131 Drives Degradation of STING-TBK1 Pathway Proteins and Negatively Regulates Antiviral Innate Immunity. J Virol. 2022 Oct 3:e0068222.
4. Zhi L, Wang W, Zheng J, Liu S, Zhou S, Qin Q, Huang Y**, Huang X*. Grouper TRIM23 exerts antiviral activity against iridovirus and nodavirus. Front Immunol. 2022, 13:985291.
5. Guo X, Wang W, Zheng Q, Qin Q, Huang Y**, Huang X*. Comparative transcriptomic analysis reveals different host cell responses to Singapore grouper iridovirus and red-spotted grouper nervous necrosis virus. Fish Shellfish Immunol. 2022 Sep;128:136-147.
6. Wang W, Zhang Y, Guo X, Xu W, Qin Q, Huang Y**, Huang X*. Singapore grouper iridovirus infection counteracts poly I:C induced antiviral immune response in vitro. Fish Shellfish Immunol. 2023 Apr;135:108685.
7. Zhang Y, Wang L, Zheng J, Huang L, Wang S, Huang X, Qin Q*, Huang Y*. Grouper Interferon-Induced Transmembrane Protein 1 Inhibits Iridovirus and Nodavirus Replication by Regulating Virus Entry and Host Lipid Metabolism. Front Immunol. 2021 Mar 9;12:636806.
8. Liu ZT, Zhang X, Zhang Y, Qin QW, Huang XH, Huang YH. Establishment of a cell line from the head kidney of giant grouper (Epinephelus lanceolatus) and its susceptibility to fish viruses. Aquaculture Reports. 2021, 21: 100899.
9. Huang YH, Huang LW, Zhang Y, Zheng Q, Xu LW, Qin QW, Huang XH, Development of a sea perch (Lateolabrax japonicus) fry cell line and its application to the study of fish virus-host interactions. Aquaculture. 2021, 736127.
10. Huang XH, Wei JG, Zheng Q, Zhang Y, Zhu WB, Liu JC, Hou YX, Qin QW, Huang YH. Isolation, identification and genomic analysis of an ISKNV-type megalocytivirus from spotted knifejaw (Oplegnathus punctatus). Aquaculture. 2021, 532: 736032.
11. Huang Y, Zhang Y, Zheng J, Wang L, Qin Q, Huang X. Metabolic profiles of fish nodavirus infection in vitro: RGNNV induced and exploited cellular fatty acid synthesis for virus infection. Cell Microbiol. 2020 Sep;22(9):e13216.
12. Huang Y, Zhang Y, Liu Z, Liu C, Zheng J, Qin Q, Huang X. Autophagy Participates in Lysosomal Vacuolation-Mediated Cell Death in RGNNV-Infected Cells. Front Microbiol. 2020 Apr 30;11:790.
13. Lv S, Zhang Y, Zheng J, Huang X, Huang Y**, Qin Q*. Negative regulation of the interferon response by finTRIM82 in the orange spotted grouper. Fish Shellfish Immunol. 2019, 88:391-402.
14. Zhang Y, Wang L, Huang X, Wang S, Huang Y**, Qin Q*. Fish Cholesterol 25-Hydroxylase Inhibits Virus Replication via Regulating Interferon Immune Response or Affecting Virus Entry. Front Immunol. 2019, 10:322.
15. Liu J, Huang Y**, Huang X, Li C, Ni SW, Yu Y, Qin Q*. Grouper DDX41 exerts antiviral activity against fish iridovirus and nodavirus infection. Fish Shellfish Immunol. 2019, 91:40-49.
16. Huang Y, Zhang J, Ouyang Z, Liu J, Zhang Y, Hu Y, Huang X, Qin Q*. Grouper MAVS functions as a crucial antiviral molecule against nervous necrosis virus infection. Fish Shellfish Immunol. 2018.72:14-22.
17. Liu J, Huang X, Yu Y, Zhang J, Ni S, Hu Y, Huang Y**, Qin Q*. Fish DDX3X exerts antiviral function against grouper nervous necrosis virus infection. Fish Shellfish Immunol. 2017 Dec;71:95-104.
18. Yu Y, Huang X, Liu J, Zhang J, Hu Y, Yang Y, Huang Y**, Qin Q. Fish TRIM32 functions as a critical antiviral molecule against iridovirus and nodavirus. Fish Shellfish Immunol. 2017 Jan;60:33-43.
19. Huang Y, Zhang J, Liu J, Hu Y, Ni S, Yang Y, Yu Y, Huang X, Qin Q. Fish TRIM35 negatively regulates the interferon signaling pathway in response to grouper nodavirus infection. Fish Shellfish Immunol. 2017, 69:142-152.
20. Huang Y, Yang M, Yu Y, Yang Y, Zhou L, Huang X, Qin Q. Grouper TRIM13 exerts negative regulation of antiviral immune response against nodavirus. Fish Shellfish Immunol. 2016, 55:106-15.
21. Huang Y, Yu Y, Yang Y, Yang M, Zhou L, Huang X, Qin Q. Fish TRIM8 exerts antiviral roles through regulation of the proinflammatory factors and interferon signaling. Fish Shellfish Immunol. 2016, 54:435-44.
22. Huang Y, Yu Y, Yang Y, Yang M, Zhou L, Huang X, Qin Q. Antiviral function of grouper MDA5 against iridovirus and nodavirus. Fish Shellfish Immunol. 2016, 54:188-96.
23. Huang Y, Ouyang Z, Wang W, Yu Y, Li P, Zhou S, Wei S, Wei J, Huang X, Qin Q. Antiviral role of grouper STING against iridovirus infection. Fish Shellfish Immunol. 2015, 47(1):157-67.
24. Huang Y, Huang X, Cai J, OuYang Z, Wei S, Wei J, Qin Q. Identification of orange-spotted grouper (Epinephelus coioides) interferon regulatory factor 3 involved in antiviral immune response against fish RNA virus. Fish Shellfish Immunol. 2015, 42(2):345-52.
25. Huang Y, Huang X, Yang Y, Wang W, Yu Y, Qin Q. Involvement of fish signal transducer and activator of transcription 3 (STAT3) in nodavirus infection induced cell death. Fish Shellfish Immunol. 2015, 43(1):241-8.
26. Huang YH, Huang XH, Ouyang ZL, Wei SN, Guo CY, Qin QW. Development of a new cell line from the snout of giant grouper, Epinephelus lanceolatus (Bloch), and its application in iridovirus and nodavirus pathogenesis. Aquaculture. 2014, 432: 265-272.
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在这里,只要你相信“天道酬勤”,你就一定会“鱼跃阔海”!